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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TACC1
All Species:
5.76
Human Site:
T250
Identified Species:
12.67
UniProt:
O75410
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75410
NP_001116296.1
805
87794
T250
I
G
G
E
F
S
D
T
N
A
A
V
E
G
T
Chimpanzee
Pan troglodytes
XP_001171659
806
87880
N251
G
G
E
F
S
D
T
N
A
A
V
E
G
T
P
Rhesus Macaque
Macaca mulatta
XP_001094596
713
77960
T182
P
E
E
L
D
E
N
T
S
P
S
S
L
G
G
Dog
Lupus familis
XP_848665
800
87410
T248
T
I
G
E
F
L
E
T
D
I
A
L
E
G
T
Cat
Felis silvestris
Mouse
Mus musculus
Q6Y685
774
83933
K240
P
K
P
V
S
L
R
K
K
M
A
P
E
P
E
Rat
Rattus norvegicus
Q4KLH6
1403
160982
K528
A
L
E
K
K
T
S
K
D
N
T
K
T
K
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506072
798
87999
D245
A
S
Y
P
F
N
P
D
N
F
D
E
N
T
N
Chicken
Gallus gallus
XP_428807
620
67438
E89
R
G
L
S
G
H
G
E
L
Q
G
G
E
Q
R
Frog
Xenopus laevis
Q9PTG8
931
102522
T306
A
D
S
T
C
E
G
T
S
D
A
Q
S
P
L
Zebra Danio
Brachydanio rerio
XP_694073
852
95238
N298
P
L
N
G
V
D
P
N
E
V
D
D
D
P
P
Tiger Blowfish
Takifugu rubipres
NP_001011696
863
95190
Q302
T
A
V
N
S
Y
E
Q
T
I
E
E
Q
E
L
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
84.7
85.5
N.A.
73.9
20.8
N.A.
69.8
50
27
42.6
38.8
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
85.8
91.1
N.A.
81.6
32.6
N.A.
78.1
59
44.1
55
53.8
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
13.3
53.3
N.A.
13.3
0
N.A.
13.3
13.3
13.3
0
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
33.3
73.3
N.A.
13.3
20
N.A.
20
13.3
20
6.6
13.3
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
28
10
0
0
0
0
0
0
10
19
37
0
0
0
0
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
10
19
10
10
19
10
19
10
10
0
0
% D
% Glu:
0
10
28
19
0
19
19
10
10
0
10
28
37
10
10
% E
% Phe:
0
0
0
10
28
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
10
28
19
10
10
0
19
0
0
0
10
10
10
28
10
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
10
0
0
0
0
0
0
0
19
0
0
0
0
0
% I
% Lys:
0
10
0
10
10
0
0
19
10
0
0
10
0
10
0
% K
% Leu:
0
19
10
10
0
19
0
0
10
0
0
10
10
0
19
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
10
10
0
10
10
19
19
10
0
0
10
0
19
% N
% Pro:
28
0
10
10
0
0
19
0
0
10
0
10
0
28
19
% P
% Gln:
0
0
0
0
0
0
0
10
0
10
0
10
10
10
0
% Q
% Arg:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% R
% Ser:
0
10
10
10
28
10
10
0
19
0
10
10
10
0
0
% S
% Thr:
19
0
0
10
0
10
10
37
10
0
10
0
10
19
19
% T
% Val:
0
0
10
10
10
0
0
0
0
10
10
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _